The HPV vaccinations used for prevention of HPV, genital warts infection and cancer in subsequent conditions in young girls and boys under 15 years of age. Now the new research has shown that 2 doses of the vaccination are just as effective as three doses in preventing genital warts.

Last year CDC (Centers for Disease Control and Prevention) urged that all children under 15 years old receive only 2 doses of the HPV vaccine, thus the new research is backing this allegation of CDC. The research also highlights on the effectiveness of the vaccine.


The Centers for Disease Control and Prevention & World health organisation based the new two dose schedule primarily on immunogenicity results, but there was very little research on the effectiveness of the doses that recommendation has been by the experts.  the study’s lead author, in a recent statement.  The study lead author Ms Rebecca Perkins, in a recent statement said that “This study validates the new recommendations and allows us to confidently move forward with the 2 dose schedule for the prevention of genital warts.

She later added that for the study, the team researchers from the Boston University Medical center took the samples from 400 thousand girls across the country to measure the rate of genital warts based on the number of vaccinations the girls received. There was no significant difference found in protection from genital warts in girls that received 3 shots compared to those who received only 2 shots

It can also be noted that this study was only focused on the frequency of of genital warts in young girls who received the HPV vaccination and it was regardless of the occurrence of HPV-related cancer in young girls who received different versions of the vaccine. These finding has also confirmed the declined rate of HPV genital warts (mainly in women), since the introduction of the vaccine.

The human papillomavirus consist of a group with over 200 viruses, out of these, bout 40 spread easily from skin and mucous membrane via sexual contact. Most of the viruses are also not of a high risk, causing only alarm, yet harmless warts on the genitals. Having said that, of these 40, at least 13 can cause cancer.These virus is known to cause cervical, vulvar, vaginal, penile, anal, mouth, and throat cancers.

While the results are useful in understanding the nature of the virus, experts believe that the research work are mere stepping stone into understanding two-dose HPV vaccines, and more research will be necessary.

Source: Perkins RB, Lin M, et al. Impact of Number of Human Papillomavirus Vaccine Doses on Genital Warts Diagnoses Among a National Cohort of U.S. Adolescents. STD Journal . 2017

https://www.cdc.gov/

http://www.who.int/mediacentre/factsheets/fs110/en/